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wnt3 plasmid  (Addgene inc)
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Addgene inc wnt3 plasmid
Fig. 3 Downregulation of <t>WNT3</t> enhances 5FU efficacy in 5FU-resistant OSCC cells. A, B RT-qPCR and western blot evaluations of WNT3 expression post-knockdown in 5FU-R cells. C, D Decreased IC50 of 5FU in 5FU-R cells after WNT3 knockdown. E, F Inhibited proliferation under 5FU exposure in 5FU-R cells after transfection with siWNT3. G and K Reduced colony-forming potential under 5FU exposure in 5FU-R cells after transfection with siWNT3. H and L Increased apoptosis under 5FU exposure in 5FU-R cells following WNT3 knockdown. I and M Decreased wound-healing (100×) under 5FU exposure in 5FU-R cells after WNT3 knockdown. J and N Diminished migration and invasion (100×) under 5FU exposure in 5FU-R cells after WNT3 knockdown
Wnt3 Plasmid, supplied by Addgene inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/wnt3 plasmid/product/Addgene inc
Average 92 stars, based on 1 article reviews
wnt3 plasmid - by Bioz Stars, 2026-02
92/100 stars
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nktr-35872  (Nektar Inc)
90
Nektar Inc nktr-35872
Fig. 3 Downregulation of <t>WNT3</t> enhances 5FU efficacy in 5FU-resistant OSCC cells. A, B RT-qPCR and western blot evaluations of WNT3 expression post-knockdown in 5FU-R cells. C, D Decreased IC50 of 5FU in 5FU-R cells after WNT3 knockdown. E, F Inhibited proliferation under 5FU exposure in 5FU-R cells after transfection with siWNT3. G and K Reduced colony-forming potential under 5FU exposure in 5FU-R cells after transfection with siWNT3. H and L Increased apoptosis under 5FU exposure in 5FU-R cells following WNT3 knockdown. I and M Decreased wound-healing (100×) under 5FU exposure in 5FU-R cells after WNT3 knockdown. J and N Diminished migration and invasion (100×) under 5FU exposure in 5FU-R cells after WNT3 knockdown
Nktr 35872, supplied by Nektar Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nktr-35872/product/Nektar Inc
Average 90 stars, based on 1 article reviews
nktr-35872 - by Bioz Stars, 2026-02
90/100 stars
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Fig. 3 Downregulation of WNT3 enhances 5FU efficacy in 5FU-resistant OSCC cells. A, B RT-qPCR and western blot evaluations of WNT3 expression post-knockdown in 5FU-R cells. C, D Decreased IC50 of 5FU in 5FU-R cells after WNT3 knockdown. E, F Inhibited proliferation under 5FU exposure in 5FU-R cells after transfection with siWNT3. G and K Reduced colony-forming potential under 5FU exposure in 5FU-R cells after transfection with siWNT3. H and L Increased apoptosis under 5FU exposure in 5FU-R cells following WNT3 knockdown. I and M Decreased wound-healing (100×) under 5FU exposure in 5FU-R cells after WNT3 knockdown. J and N Diminished migration and invasion (100×) under 5FU exposure in 5FU-R cells after WNT3 knockdown

Journal: BMC cancer

Article Title: WNT3 promotes chemoresistance to 5-Fluorouracil in oral squamous cell carcinoma via activating the canonical β-catenin pathway.

doi: 10.1186/s12885-024-12318-2

Figure Lengend Snippet: Fig. 3 Downregulation of WNT3 enhances 5FU efficacy in 5FU-resistant OSCC cells. A, B RT-qPCR and western blot evaluations of WNT3 expression post-knockdown in 5FU-R cells. C, D Decreased IC50 of 5FU in 5FU-R cells after WNT3 knockdown. E, F Inhibited proliferation under 5FU exposure in 5FU-R cells after transfection with siWNT3. G and K Reduced colony-forming potential under 5FU exposure in 5FU-R cells after transfection with siWNT3. H and L Increased apoptosis under 5FU exposure in 5FU-R cells following WNT3 knockdown. I and M Decreased wound-healing (100×) under 5FU exposure in 5FU-R cells after WNT3 knockdown. J and N Diminished migration and invasion (100×) under 5FU exposure in 5FU-R cells after WNT3 knockdown

Article Snippet: 293T cells at 80% confluence were co-transfected with the WNT3 plasmid or its control vector with Top-flash (Addgene, USA) and Renilla plasmids (Promega, USA) using the Lipofectamine 2000.

Techniques: Quantitative RT-PCR, Western Blot, Expressing, Knockdown, Transfection, Migration